Bemcentinib (R428)
Product Specifications
CAS Number
1037624-75-1
Synonyms
BGB324
SKU
C08899-1mg
Target
Axl
Applications
Protein Tyrosine Kinase
Smiles
C1CCN (C1) C2CCC3=C (CC2) C=C (C=C3) NC4=NN (C (=N4) N) C5=NN=C6C (=C5) CCCC7=CC=CC=C76
Molecular Formula
C30H34N8
Additionnal Information
Bemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective) .
Storage Conditions
2 years -80 in solvent
Available Sizes
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