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Fexagratinib (AZD4547)

Product Specifications

CAS Number

1035270-39-3

Synonyms

ABSK 091

SKU

C08869-5mg

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1CN (CC (N1) C) C2=CC=C (C=C2) C (=O) NC3=NNC (=C3) CCC4=CC (=CC (=C4) OC) OC

Molecular Formula

C26H33N5O3

Additionnal Information

Fexagratinib (AZD4547, ABSK 091) is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2 (KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.

Storage Conditions

2 years -80 in solvent

Available Sizes

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