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Lonafarnib (SCH66336)

Product Specifications

CAS Number

193275-84-2

SKU

C08866-5mg

Target

Transferase

Applications

Metabolism

Smiles

C1CN (CCC1CC (=O) N2CCC (CC2) C3C4=C (CCC5=C3N=CC (=C5) Br) C=C (C=C4Br) Cl) C (=O) N

Molecular Formula

C27H31Br2ClN4O2

Additionnal Information

Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.

Storage Conditions

2 years -80 in solvent

Available Sizes

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