Tofacitinib
Product Specifications
CAS Number
477600-75-2
Synonyms
CP-690550, Tasocitinib
SKU
C08859-5mg
Target
JAK
Applications
Angiogenesis
Smiles
CC1CCN (CC1N (C) C2=NC=NC3=C2C=CN3) C (=O) CC#N
Molecular Formula
C16H20N6O
Additionnal Information
Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
R1495-03H 200 µL
RENT1, NT (Regulator of Nonsense Transcripts 1, ATP-dependent Helicase RENT1, Nonsense mRNA Reducing Factor 1, NORF1, Up-frameshift Suppressor 1 Homolog, hUpf1, KIAA0221, UPF1) discontinued
Sign In for Pricing
View Details 127895-ML550 100 µL
HLA Class 2 Antigen DRB1 (HLA Class II Histocompatibility Antigen DRB1-1 beta Chain, HLA-DR1B, HLA-DRB1, HLA-DRB1*, HLA-DRB, DR1, DR-1, DRB1, DRw10, FLJ75017, FLJ76359, MHC Class II Antigen DRB1*1, SS1) (MaxLight 550)
Sign In for Pricing
View Details