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3-MA (3-Methyladenine)

Product Specifications

CAS Number

5142-23-4

Synonyms

NSC 66389

SKU

C08842-50mg

Target

Autophagy

Applications

Autophagy

Smiles

CN1C=NC (=N) C2=C1N=CN2

Molecular Formula

C6H7N5

Additionnal Information

3-MA (3-Methyladenine) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. Solutions are unstable and should be fresh-prepared.

Available Sizes

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