Tivantinib

Product Specifications

CAS Number

905854-02-6

Synonyms

ARQ 197

SKU

C08830-10mg

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

C1CC2=C3C (=CC=C2) C (=CN3C1) C4C (C (=O) NC4=O) C5=CNC6=CC=CC=C65

Molecular Formula

C23H19N3O2

Additionnal Information

Tivantinib is the first non-ATP-competitive c-Met inhibitor with Ki of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Tivantinib (ARQ 197) induces a G2/M arrest and apoptosis.

Storage Conditions

2 years -80 in solvent

Available Sizes

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