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AMG-458

Product Specifications

CAS Number

913376-83-7

SKU

C08824-5mg

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C (=O) N (N1CC (C) (C) O) C2=CC=CC=C2) C (=O) NC3=NC=C (C=C3) OC4=C5C=CC (=CC5=NC=C4) OC

Molecular Formula

C30H29N5O5

Additionnal Information

AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.

Storage Conditions

2 years -80 in solvent

Available Sizes

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