PHA-767491 HCl
Product Specifications
CAS Number
942425-68-5
Synonyms
CAY10572, NMS 1116354
SKU
C08819-10mg
Target
CDK
Applications
Cell Cycle
Smiles
C1CNC (=O) C2=C1NC (=C2) C3=CC=NC=C3.Cl
Molecular Formula
C12H11N3O.HCl
Additionnal Information
PHA-767491 (CAY10572, NMS 1116354) HCl is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell-free assays, respectively.It displays ~20-fold selectivity against CDK1/2 and GSK3-β, 50-fold selectivity against MK2 and CDK5, 100-fold selectivity against PLK1 and CHK2.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6413996-01 0.1 mL
DGCR8 (DiGeorge Syndrome Critical Region 8, Gy1, pasha, DGCRK6, C22orf12) (MaxLight 550)
Sign In for Pricing
View Details MBS6413996-02 5x 0.1 mL
DGCR8 (DiGeorge Syndrome Critical Region 8, Gy1, pasha, DGCRK6, C22orf12) (MaxLight 550)
Sign In for Pricing
View Details