AV-412 free base
Product Specifications
CAS Number
451492-95-8
Synonyms
MP-412 free base
SKU
C08812-2mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C (C) (C) C#CC2=CC3=C (C=C2NC (=O) C=C) C (=NC=N3) NC4=CC (=C (F) C=C4) Cl
Molecular Formula
C27H28ClFN6O
Additionnal Information
AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.51, 0.79, 2.30, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.
Storage Conditions
2 years -80 in solvent
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