AV-412 free base

Product Specifications

CAS Number

451492-95-8

Synonyms

MP-412 free base

SKU

C08812-2mg

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C (C) (C) C#CC2=CC3=C (C=C2NC (=O) C=C) C (=NC=N3) NC4=CC (=C (F) C=C4) Cl

Molecular Formula

C27H28ClFN6O

Additionnal Information

AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.51, 0.79, 2.30, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

Storage Conditions

2 years -80 in solvent

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