AG-1478

Product Specifications

CAS Number

153436-53-4,175178-82-2

Synonyms

Tyrphostin AG-1478, NSC 693255

SKU

C08808-5mg

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=CC=C3) Cl) OC

Molecular Formula

C16H14ClN3O2

Additionnal Information

AG-1478 is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase IIIα (PI4KA) .