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Ibrutinib

Product Specifications

CAS Number

936563-96-1

Synonyms

PCI-32765

SKU

C08774-5mg

Target

BTK

Applications

Protein Tyrosine Kinase

Smiles

C=CC (=O) N1CCCC (C1) N2C3=NC=NC (=C3C (=N2) C4=CC=C (C=C4) OC5=CC=CC=C5) N

Molecular Formula

C25H24N6O2

Additionnal Information

Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.

Storage Conditions

2 years -80 in solvent

Available Sizes

Frequently Asked Questions

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