Tubacin

Product Specifications

CAS Number

537049-40-4

SKU

C08383-5mg

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

C1C (OC (OC1C2=CC=C (C=C2) CO) C3=CC=C (C=C3) NC (=O) CCCCCCC (=O) NO) CSC4=NC (=C (O4) C5=CC=CC=C5) C6=CC=CC=C6

Molecular Formula

C41H43N3O7S

Additionnal Information

Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM in a cell-free assay, approximately 350-fold selectivity over HDAC1. Tubacin reduces the replication of the Japanese Encephalitis Virus via the decrease of viral RNA synthesis.