Sapitinib (AZD8931)
Product Specifications
CAS Number
848942-61-0
SKU
C08346-50mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CNC (=O) CN1CCC (CC1) OC2=C (C=C3C (=C2) C (=NC=N3) NC4=C (C (=CC=C4) Cl) F) OC
Molecular Formula
C23H25ClFN5O3
Additionnal Information
Sapitinib (AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell-free assays, more potent against NSCLC cell, 100-fold more selective for the ErbB family than MNK1 and Flt. Phase 2.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1023464-01 0.02 mg (E-Coli)
Recombinant Geobacter uraniireducens Protein grpE (grpE)
Sign In for Pricing
View Details MBS1023464-02 0.1 mg (E-Coli)
Recombinant Geobacter uraniireducens Protein grpE (grpE)
Sign In for Pricing
View Details MBS1023464-03 0.02 mg (Yeast)
Recombinant Geobacter uraniireducens Protein grpE (grpE)
Sign In for Pricing
View Details MBS1023464-04 0.1 mg (Yeast)
Recombinant Geobacter uraniireducens Protein grpE (grpE)
Sign In for Pricing
View Details MBS1023464-05 0.02 mg (Baculovirus)
Recombinant Geobacter uraniireducens Protein grpE (grpE)
Sign In for Pricing
View Details