Disulfiram

Product Specifications

CAS Number

97-77-8

Synonyms

NSC 190940, Tetraethylthiuram disulfide, TETD

SKU

C07975-50mg

Target

Dehydrogenase

Applications

Metabolism

Smiles

CCN (CC) C (=S) SSC (=S) N (CC) CC

Molecular Formula

C10H20N2S4

Additionnal Information

Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH) with IC50 of 0.15 μM and 1.45 μM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD) .