Tie2 kinase inhibitor 1

948557-43-5

C07904-10mg

Tie-2

Protein Tyrosine Kinase

COC1=CC2=C (C=C1) C=C (C=C2) C3=C (NC (=N3) C4=CC=C (C=C4) S (=O) C) C5=CC=NC=C5

C26H21N3O2S

Tie2 kinase inhibitor 1 is an optimized compound of SB-203580, selective to Tie2 with IC50 of 0.25 μM, 200-fold more potent than p38.

2 years -80 in solvent