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TCS7010 (Aurora A Inhibitor I)

Product Specifications

CAS Number

1158838-45-9

Synonyms

TC-S 7010

SKU

C07806-50mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CCN1CCN (CC1) C (=O) CC2=CC=C (C=C2) NC3=NC=C (C (=N3) NC4=CC=C (C=C4) C (=O) NC5=CC=CC=C5Cl) F

Molecular Formula

C31H31ClFN7O2

Additionnal Information

TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.

Storage Conditions

2 years -80 in solvent

Available Sizes

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