What is the catalog number for Amarogentin?

The catalog number for Amarogentin is C07674.

What sizes are available for Amarogentin?

Amarogentin is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does Amarogentin come in?

Amarogentin is available in 2 different pack sizes.

Is Amarogentin in stock?

Amarogentin is currently made to order / not held in immediate stock. Contact us for lead time.

Amarogentin

Product Specifications

CAS Number

21018-84-8

Synonyms

AG

SKU

C07674-5mg

Target

Taste Receptor

Applications

GPCR & G Protein

Smiles

OCC1OC (OC2OC=C3C (CCOC3=O) C2C=C) C (OC (=O) C4=C (O) C=C (O) C=C4C5=CC=CC (=C5) O) C (O) C1O

Molecular Formula

C29H30O13

Additionnal Information

Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. Amarogentin induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. Amarogentin (AG) interacts with the α2 subunit of AMP-activated protein kinase (AMPK) and activates the trimeric kinase with EC50 of 277 pM.