PD173074
Product Specifications
CAS Number
219580-11-7
SKU
C07667-5mg
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CCN (CC) CCCCNC1=NC2=NC (=C (C=C2C=N1) C3=CC (=CC (=C3) OC) OC) NC (=O) NC (C) (C) C
Molecular Formula
C28H41N7O3
Additionnal Information
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
7642-20 20 µg
Bromodomain Testis-specific Protein (BrdT, domain 257-382 aa), human recombinant
Sign In for Pricing
View Details 
034051-ML490 100 µL
CNOT3, NT (CNOT3, KIAA0691, LENG2, NOT3, CCR4-NOT transcription complex subunit 3, CCR4-associated factor 3, Leukocyte receptor cluster member 2) (MaxLight 490) discontinued
Sign In for Pricing
View Details 