Leflunomide

Product Specifications

CAS Number

75706-12-6

Synonyms

HWA486, RS-34821, SU101

SKU

C07653-100mg

Target

Dehydrogenase

Applications

Metabolism

Smiles

CC1=C (C=NO1) C (=O) NC2=CC=C (C=C2) C (F) (F) F

Molecular Formula

C12H9F3N2O2

Additionnal Information

Leflunomide is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH) . Leflunomide is also an agonist of the AhR.