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TMZ (Temozolomide)

Product Specifications

CAS Number

85622-93-1

Synonyms

NSC 362856, CCRG 81045, Methazolastone

SKU

C07644-25mg

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

CN1C (=O) N2C=NC (=C2N=N1) C (=O) N

Molecular Formula

C6H6N6O2

Additionnal Information

TMZ (Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.

Storage Conditions

In dark and seal

Available Sizes

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