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Letrozole

Product Specifications

CAS Number

112809-51-5

Synonyms

CGS 20267

SKU

C07642-25mg

Target

Aromatase

Applications

Endocrinology & Hormones

Smiles

C1=CC (=CC=C1C#N) C (C2=CC=C (C=C2) C#N) N3C=NC=N3

Molecular Formula

C17H11N5

Additionnal Information

Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies. Letrozole induces autophagy.

Storage Conditions

2 years -80 in solvent

Available Sizes

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