Doxorubicin (DOX) HCl

Product Specifications

CAS Number

25316-40-9

Synonyms

Adriamycin, NSC 123127, Hydroxydaunorubicin HCl

SKU

C07616-10mg

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

CC1C (C (CC (O1) OC2CC (CC3=C2C (=C4C (=C3O) C (=O) C5=C (C4=O) C (=CC=C5) OC) O) (C (=O) CO) O) N) O.Cl

Molecular Formula

C27H29NO11.HCl

Additionnal Information

Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease.