ABT-751 (E7010)
Product Specifications
CAS Number
141430-65-1
SKU
C07575-10mg
Target
Microtubule Associated
Applications
Cytoskeletal Signaling
Smiles
COC1=CC=C (C=C1) S (=O) (=O) NC2=C (N=CC=C2) NC3=CC=C (C=C3) O
Molecular Formula
C18H17N3O4S
Additionnal Information
ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.
Storage Conditions
2 years -80 in solvent
Available Sizes
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