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Tanespimycin (17-AAG)

Product Specifications

CAS Number

75747-14-7

Synonyms

CP127374, NSC-330507, KOS 953

SKU

C07552-25mg

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CC1CC (C (C (C=C (C (C (C=CC=C (C (=O) NC2=CC (=O) C (=C (C1) C2=O) NCC=C) C) OC) OC (=O) N) C) C) O) OC

Molecular Formula

C31H43N3O8

Additionnal Information

Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.

Storage Conditions

2 years -80 in solvent

Available Sizes

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