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Alisertib (MLN8237)

Product Specifications

CAS Number

1028486-01-2

SKU

C07547-5mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

COC1=C (C (=CC=C1) F) C2=NCC3=CN=C (N=C3C4=C2C=C (C=C4) Cl) NC5=CC (=C (C=C5) C (=O) O) OC

Molecular Formula

C27H20ClFN4O4

Additionnal Information

Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. Phase 3.

Storage Conditions

2 years -80 in solvent

Available Sizes

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