Alisertib (MLN8237)

Product Specifications

CAS Number

1028486-01-2

SKU

C07547-5mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

COC1=C (C (=CC=C1) F) C2=NCC3=CN=C (N=C3C4=C2C=C (C=C4) Cl) NC5=CC (=C (C=C5) C (=O) O) OC

Molecular Formula

C27H20ClFN4O4

Additionnal Information

Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. Phase 3.

Storage Conditions

2 years -80 in solvent

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

NBP2-71152MFV610 0.1 mL

Mouse Monoclonal LMAN1 Antibody (OTI1A8) [mFluor Violet 610 SE]

View Details

EK346694 96 Well

Rabbit NOX4 (Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4) ValidElisa Kit

View Details

VCA91254-01 500 mg

5- (Azepan-2-ylidene) -2,2-dimethyl-1,3-dioxane-4,6-dione

View Details

VCA91254-02 1000 mg

5- (Azepan-2-ylidene) -2,2-dimethyl-1,3-dioxane-4,6-dione

View Details

MBS1099147-01 0.02 mg (E-Coli)

Recombinant Wound tumor virus Suppressor of RNA-mediated gene silencing

View Details

MBS1099147-02 0.02 mg (Yeast)

Recombinant Wound tumor virus Suppressor of RNA-mediated gene silencing

View Details