Triciribine (API-2)

Product Specifications

CAS Number

35943-35-2

Synonyms

NSC 154020, VD-0002, vqd-002, TCN

SKU

C07534-5mg

Target

Akt

Applications

PI3K/Akt/mTOR

Smiles

CN1C2=NC=NC3=C2C (=CN3C4C (C (C (O4) CO) O) O) C (=N1) N

Molecular Formula

C13H16N6O4

Additionnal Information

Triciribine (API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.