KU-55933

Product Specifications

CAS Number

587871-26-9

Synonyms

ATM Kinase Inhibitor

SKU

C07509-5mg

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

C1COCCN1C2=CC (=O) C=C (O2) C3=C4C (=CC=C3) SC5=CC=CC=C5S4

Molecular Formula

C21H17NO3S2

Additionnal Information

KU-55933 is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. KU‐55933 (ATM Kinase Inhibitor) inhibits the activation of autophagy‐initiating kinase ULK1 and results in a significant decrease of autophagy.