What is the catalog number for Crizotinib?

The catalog number for Crizotinib is C07488.

What sizes are available for Crizotinib?

Crizotinib is available in the following size(s): 5 mg, 10 mM / 1 mL, 50 mg, 200 mg, 1 g.

How many pack sizes does Crizotinib come in?

Crizotinib is available in 5 different pack sizes.

Is Crizotinib in stock?

Crizotinib is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Crizotinib?

Crizotinib is requires dry ice shipping.

Crizotinib

Product Specifications

CAS Number

877399-52-5

Synonyms

PF-02341066

SKU

C07488-5mg

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

CC (C1=C (C=CC (=C1Cl) F) Cl) OC2=C (N=CC (=C2) C3=CN (N=C3) C4CCNCC4) N

Molecular Formula

C21H22Cl2FN5O

Additionnal Information

Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.