Olaparib (AZD2281)
Product Specifications
CAS Number
763113-22-0
Synonyms
Ku-0059436
SKU
C07481-10mg
Target
PARP
Applications
DNA Damage/DNA Repair
Smiles
C1CC1C (=O) N2CCN (CC2) C (=O) C3=C (C=CC (=C3) CC4=NNC (=O) C5=CC=CC=C54) F
Molecular Formula
C24H23FN4O3
Additionnal Information
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
250669-AP 100 µL
PTK7 (PTK7 Protein Tyrosine Kinase 7, CCK4) (AP) discontinued
Sign In for Pricing
View Details 043758-ML750 100 µL
VIPR1, CT (VIPR1, Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, VPAC1) (MaxLight 750) discontinued
Sign In for Pricing
View Details 
