Olaparib (AZD2281)
Product Specifications
CAS Number
763113-22-0
Synonyms
Ku-0059436
SKU
C07481-10mg
Target
PARP
Applications
DNA Damage/DNA Repair
Smiles
C1CC1C (=O) N2CCN (CC2) C (=O) C3=C (C=CC (=C3) CC4=NNC (=O) C5=CC=CC=C54) F
Molecular Formula
C24H23FN4O3
Additionnal Information
Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
Storage Conditions
2 years -80 in solvent
Available Sizes
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