Sunitinib malate
Product Specifications
CAS Number
341031-54-7
Synonyms
SU11248 malate
SKU
C07463-100mg
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
CCN (CC) CCNC (=O) C1=C (NC (=C1C) C=C2C3=C (C=CC (=C3) F) NC2=O) C.C (C (C (=O) O) O) C (=O) O
Molecular Formula
C22H27FN4O2.C4H6O5
Additionnal Information
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.
Storage Conditions
2 years -80 in solvent
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
H3968 96 Tests
Synaptophysin-Like protein 2 (SYPL2) Rabbit ELISA Kit
Sign In for Pricing
View Details TRV-0064182-01 24 Tests
ELISA Kit for Hippocalcin Like Protein 1 (HPCAL1)
Sign In for Pricing
View Details TRV-0064182-02 48 Tests
ELISA Kit for Hippocalcin Like Protein 1 (HPCAL1)
Sign In for Pricing
View Details TRV-0064182-03 96 Tests
ELISA Kit for Hippocalcin Like Protein 1 (HPCAL1)
Sign In for Pricing
View Details TRV-0064182-04 5x 96 Tests
ELISA Kit for Hippocalcin Like Protein 1 (HPCAL1)
Sign In for Pricing
View Details TRV-0064182-05 10x 96 Tests
ELISA Kit for Hippocalcin Like Protein 1 (HPCAL1)
Sign In for Pricing
View Details