Sorafenib tosylate
Product Specifications
CAS Number
475207-59-1
Synonyms
BAY 43-9006 tosylate, NSC-724772 tosylate
SKU
C07461-50mg
Target
PDGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC=C (C=C1) S (=O) (=O) O.CNC (=O) C1=NC=CC (=C1) OC2=CC=C (C=C2) NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F
Molecular Formula
C21H16ClF3N4O3.C7H8O3S
Additionnal Information
Sorafenib tosylate is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
Storage Conditions
2 years -80 in solvent
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6388142-01 0.1 mL
OTUB2 (Ubiquitin Thioesterase OTUB2, Deubiquitinating Enzyme OTUB2, OTU Domain-containing Ubiquitin Aldehyde-binding Protein 2, Otubain-2, Ubiquitin-specific-processing Protease OTUB2, C14orf137, OTB2, OTU2, FLJ21916, MGC3102) (Biotin)
Ask
View Details MBS6388142-02 5x 0.1 mL
OTUB2 (Ubiquitin Thioesterase OTUB2, Deubiquitinating Enzyme OTUB2, OTU Domain-containing Ubiquitin Aldehyde-binding Protein 2, Otubain-2, Ubiquitin-specific-processing Protease OTUB2, C14orf137, OTB2, OTU2, FLJ21916, MGC3102) (Biotin)
Ask
View Details 
