What is the catalog number for Cucurbitacin IIb?

The catalog number for Cucurbitacin IIb is C07405.

What sizes are available for Cucurbitacin IIb?

Cucurbitacin IIb is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does Cucurbitacin IIb come in?

Cucurbitacin IIb is available in 2 different pack sizes.

Is Cucurbitacin IIb in stock?

Cucurbitacin IIb is currently made to order / not held in immediate stock. Contact us for lead time.

Cucurbitacin IIb

Product Specifications

CAS Number

50298-90-3

Synonyms

CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A

SKU

C07405-5mg

Target

STAT

Applications

Apoptosis

Smiles

CC1 (C (C (CC2C1=CCC3C2 (C (=O) CC4 (C3 (CC (C4C (C) (C (=O) CCC (C) (C) O) O) O) C) C) C) O) O) C

Molecular Formula

C30H48O7

Additionnal Information

Cucurbitacin IIb (CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A) inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB, blocks nuclear translocation of NF-κB and decreases mRNA levels of IκBα and TNF-α. Cucurbitacin IIb exhibits anti-inflammatory activity and induces apoptosis. Cucurbitacin IIb is isolated from Hemsleya amabilis.