γ-Mangostin

Product Specifications

CAS Number

31271-07-5

Synonyms

Gamma-Mangostin

SKU

C07399-5mg

Target

5-HT Receptor

Applications

Neuronal Signaling

Smiles

CC (=CCC1=C (C2=C (C=C1O) OC3=C (C2=O) C (=C (C (=C3) O) O) CC=C (C) C) O) C

Molecular Formula

C23H24O6

Additionnal Information

γ-Mangostin (Gamma-Mangostin) is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptors antagonist, which can reduce the perfusion pressure response of rat coronary artery to 5-HT2A with an IC50 of 0.32 μM and inhibit [3H] spiperone binding to cultured rat aortic myocytes with an IC50 of 3.5 nM. Gamma-Mangostin is also an inhibitor of Transthyretin (TTR) fibrillization.