SR-717 lithium
Product Specifications
CAS Number
2375421-09-1
SKU
C07358-5mg
Target
STING
Applications
Immunology & Inflammation
Smiles
[Li]OC (=O) C1=C (NC (=O) C2=NN=C (C=C2) [N]3C=CN=C3) C=C (F) C (=C1) F
Molecular Formula
C15H8F2LiN5O3
Additionnal Information
SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.
Storage Conditions
3 years -20°C powder
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS166392-01 48 Well
Human Polyamine-modulated factor 1-binding protein 1, PMFBP1 ELISA Kit
Ask
View Details 
MBS166392-02 96 Well
Human Polyamine-modulated factor 1-binding protein 1, PMFBP1 ELISA Kit
Ask
View Details MBS166392-03 5x 96 Well
Human Polyamine-modulated factor 1-binding protein 1, PMFBP1 ELISA Kit
Ask
View Details MBS166392-04 10x 96 Well
Human Polyamine-modulated factor 1-binding protein 1, PMFBP1 ELISA Kit
Ask
View Details 
MBS6178698-01 0.1 mL
CARHSP1 (Calcium Regulated Heat Stable Protein 1, 24kD, CRHSP-24, CSDC1, MGC111446) (FITC)
Ask
View Details