A-740003
Product Specifications
CAS Number
861393-28-4
SKU
C07342-5mg
Target
P2 Receptor
Applications
Neuronal Signaling
Smiles
CC (C) (C) C (NC (=O) CC1=CC (=C (C=C1) OC) OC) N=C (NC#N) NC2=CC=CC3=C2C=CC=N3
Molecular Formula
C26H30N6O3
Additionnal Information
A-740003 is a potent, selective and competitive antagonist of P2X7 receptor with IC50 of 18 nM and 40 nM for rat and human P2X7 receptors, respectively. A-740003 potently blocks agonist-evoked IL-1β release and pore formation with IC50 of 156 nM and 92 nM in differentiated human THP-1 cells.
Storage Conditions
3 years -20°C powder
Available Sizes
Curated Selection
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