BI-671800
Product Specifications
CAS Number
1093108-50-9
Synonyms
AP-761, Cmpd A
SKU
C07211-5mg
Target
Prostaglandin Receptor
Applications
GPCR & G Protein
Smiles
CN (C) C1=C (C (=NC (=N1) CC2=CC=C (C=C2) NC (=O) C3=CC=C (C=C3) C (F) (F) F) N (C) C) CC (=O) O
Molecular Formula
C25H26F3N5O3
Additionnal Information
BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS.
Storage Conditions
3 years -20°C powder
Available Sizes
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