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CS-2660 (JNJ-38158471)

Product Specifications

CAS Number

951151-97-6

SKU

C07154-5mg

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

CCNC (=O) NC1=C (C=C (C=C1) OC2=NC=NC (=C2C=NOC) N) Cl

Molecular Formula

C15H17ClN6O3

Additionnal Information

CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM, while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.

Storage Conditions

3 years -20°C powder

Available Sizes

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