NAcM-OPT

Product Specifications

CAS Number

2089293-61-6

SKU

C07140-5mg

Target

E2 conjugating

Applications

Ubiquitin

Smiles

CCCCN1CCC (CC1) N (CC2=CC=CC=C2) C (=O) NC3=CC (=C (C=C3) Cl) Cl

Molecular Formula

C23H29Cl2N3O

Additionnal Information

NAcM-OPT is a specific, reversible and orally bioavailable inhibitor of cullin neddylation 1 (DCN1) that targets N-Acetyl-UBE2M (E2 conjugating enzyme, UBC12) interaction with DCN1 with IC50 of 79 nM.

Storage Conditions

3 years -20°C powder

Available Sizes

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