Olodanrigan (EMA401)
Product Specifications
CAS Number
1316755-16-4
Synonyms
PD-126055, (S) PD-126055
SKU
C07130-5mg
Target
Angiotensin Receptor
Applications
GPCR & G Protein
Smiles
COC1=C (C2=C (CN (C (C2) C (=O) O) C (=O) C (C3=CC=CC=C3) C4=CC=CC=C4) C=C1) OCC5=CC=CC=C5
Molecular Formula
C32H29NO5
Additionnal Information
Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R) . Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.
Storage Conditions
3 years -20°C powder
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