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FC131 (TFA)

Product Specifications

UNSPSC Description

FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity[1].

Target Antigen

CXCR; HIV

Type

Peptides

Related Pathways

Anti-infection;GPCR/G Protein;Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fc131-tfa.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C(F)(F)F)=O.O=C([C@@H](NC([C@@H](NC([C@@H](CC1=CC=C(O)C=C1)NC(CNC2=O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)N[C@H]2CC3=CC4=C(C=CC=C4)C=C3

Molecular Weight

843.85

References & Citations

[1]Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1104A/FC131-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1104A/FC131-TFA-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

842166-42-1

Available Sizes

Curated Selection

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