BAM (8-22)

CSCCC (NC (=O) C (CC1=C[NH]C2=CC=CC=C12) NC (=O) C (CC3=C[NH]C4=CC=CC=C34) NC (=O) C (CCC (O) =O) NC (=O) C5CCCN5C (=O) C (CCCNC (N) =N) NC (=O) CNC (=O) C (N) C (C) C) C (=O) NC (CC (O) =O) C (=O) NC (CC6=CC=C (O) C=C6) C (=O) NC (CCC (N) =O) C (=O) NC (CCCCN) C (=O) NC (CCCNC (N) =N) C (=O) NC (CC7=CC=C (O) C=C7) C (=O) NCC (O) =O

BAM (8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner.