Quisinostat
Product Specifications
CAS Number
875320-29-9
Synonyms
JNJ-26481585
SKU
C04836-5mg
Target
HDAC
Applications
DNA Damage/DNA Repair
Additionnal Information
Quisinostat (JNJ-26481585) is a potent and orally active second-generation inhibitor of pan-Histone Deacetylase (HDAC) . It inhibits HDAC1, HDAC2, HDAC4, HDAC10, HDAC11 with IC50s of 0.11 nM , 0.33 nM , 0.64 nM , 0.46 nM, 0.37 nM respectively. It exhibits potent in vivo antitumor activity and potential clinical use in various solid and hematologic malignancies.
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