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Siramesine

Product Specifications

CAS Number

147817-50-3

Synonyms

Lu 28-179

SKU

C04430-5mg

Target

Sigma Receptor

Applications

Neuronal Signaling

Additionnal Information

Siramesine (Lu 28-179) is a potent agonist of sigma-2 receptor (σ1R) with an IC50 of 0.12 nM, exhibiting 140-fold selectivity over sigma-1 receptors. It shows strong anxiolytic effects and induces cancer cell death, highlighting its potential anticancer activity.

Storage Conditions

2 years -20°C liquid

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