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GNF4877

Product Specifications

CAS Number

2041073-22-5

SKU

C04419-1mg

Target

DYRK

Applications

Protein Tyrosine Kinase

Additionnal Information

GNF4877 is an aminopyrazine and a potent inhibitor of GSK3β and DYRK1A with an IC50 of 16 nM and 6 nM, respectively. It blocks nuclear factor of activated T-cells (NFATc) nuclear export, promotes β-cell proliferation, and is useful for research on diabetes drug development.

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