7α,25-Dihydroxycholesterol

Product Specifications

CAS Number

64907-22-8

Synonyms

7α,25-OHC

SKU

C04381-5mg

Target

GPR

Applications

GPCR & G Protein

Additionnal Information

7α,25-Dihydroxycholesterol (7α,25-OHC) is a potent and selective endogenous agonist of the orphan G protein-coupled receptor EBI2 (GPR183) . It exhibits high potency in activating EBI2, with an EC50 of 140 pM and a Kd of 450 pM.

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