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BpV (phen)

Product Specifications

CAS Number

42494-73-5

SKU

C04357-5mg

Additionnal Information

BpV (phen), a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. bpV (phen) inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV (phen) strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ) . bpV (phen) can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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