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Pyr10

Product Specifications

CAS Number

1315323-00-2

SKU

C04327-5mg

Additionnal Information

Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca2+ entry in BRL-2H3 cells) . Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1) /Orai1 channels.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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