Ch55

Ch55 is a synthetic analog of retinoic acid that acts as a potent agonist of RAR, binding with high affinity to retinoic acid receptors RAR-α, RAR-β, and RAR-γ, while showing no binding to cellular retinoic acid binding protein (CRABP) . It demonstrates anti-fibrotic effects in preclinical models, reducing collagen deposition and hypertrophy in dermal tissues.